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Morphine sulfate tablets really should not be utilized for an prolonged length of time Except if the discomfort continues to be extreme plenty of to have to have an opioid analgesic and for which alternative cure solutions proceed for being inadequate.
In an individual bodily dependent on opioids, administration from the encouraged typical dosage on the antagonist will precipitate an acute withdrawal syndrome. The severity on the withdrawal signs or symptoms seasoned will rely on the degree of Actual physical dependence and the dose of your antagonist administered.
Focus on the availability of naloxone for that emergency cure of opioid overdose Using the affected individual and caregiver and evaluate the probable need to have for usage of naloxone, each when initiating and renewing treatment method with morphine sulfate tablets [see Warnings and Safety measures (five.two)].
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Carcinogenesis Prolonged-term research in animals To judge the carcinogenic likely of morphine haven't been carried out.